Urinary Metals Linked to Cardiovascular Risks and Mortality
Associations between Metals and Heart Health
Recent research has established significant correlations between elevated levels of specific urinary metals and an increased risk of cardiovascular disease (CVD). These metals, including cadmium, tungsten, uranium, cobalt, copper, and zinc, have been identified as potential contributors to cardiovascular complications.
Implications for Health
Studies have demonstrated that higher levels of these urinary metals are associated with a higher likelihood of developing CVD and premature mortality. Specifically, cadmium exposure has been linked to hypertension, atherosclerosis, and coronary heart disease. Tungsten and uranium have been implicated in arterial stiffness and impaired heart function. Cobalt and copper have shown adverse effects on blood pressure and lipid metabolism, while zinc deficiencies have been associated with increased CVD risk.
Understanding the Mechanisms
The mechanisms through which these urinary metals exert their negative effects on cardiovascular health are complex and still under investigation. However, research suggests that they may contribute to oxidative stress, inflammation, and impaired endothelial function. By damaging the delicate lining of blood vessels, these metals can disrupt blood flow and increase the risk of plaque formation and blood clots.
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